BDBM31883 9-cis-retinoic acid (9cRA)::ALL-TRANS-RETINOIC ACID::AT-RA::Atralin::CHEMBL38::MLS000028588::SMR000058245::TRETINOIN::Vitamin A acid::[3H]RA::[3H]Retinoic acid::[3H]Vitamin A acid::[3H]tretinoin::all-trans retinoic acid::cid_444795
SMILES CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C
InChI Key InChIKey=SHGAZHPCJJPHSC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 261 hits for monomerid = 31883
Affinity DataEC50: >0.00100nMAssay Description:Transcriptional activation of Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-9-cis RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-9-cis RA binding to Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
Affinity DataKd: >0.00100nMAssay Description:Inhibition of [3H]-9-cis RA binding to Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Agonistic activity towards retinoic acid receptor-gammaMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards human Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Dissociation constant for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKd: 0.200nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Activity at human RARgamma ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16...More data for this Ligand-Target Pair
Affinity DataEC50: 0.220nMAssay Description:Transactivation of mouse Gal4-fused RARgamma-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.300nMAssay Description:Apparent binding constant against Retinoic acid receptor gamma in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity towards cRAR-beta-2 receptor by displacing 1.1 nM 3[H]-9-cis-RAMore data for this Ligand-Target Pair
Affinity DataKd: 0.400nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity for retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 0.400nMpH: 7.9 T: 2°CAssay Description:Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...More data for this Ligand-Target Pair
TargetCellular retinoic acid-binding protein 1(Mouse)
University of Alabama At Birmingham
Curated by ChEMBL
University of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 0.400nMAssay Description:Inhibition of [3H]ATRA binding to murine Cytoplasmic retinoic acid binding protein (CRABP) type 1More data for this Ligand-Target Pair
TargetCellular retinoic acid-binding protein 1(Mouse)
University of Alabama At Birmingham
Curated by ChEMBL
University of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 0.400nMAssay Description:Binding affinity for mouse Cytoplasmic retinoic acid binding protein type 1More data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Apparent binding constant for Retinoic acid receptor beta in HeLa cellGAL-4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of [3H]RA to binding Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Transcriptional activation of retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [3H]ATRA-Hl60 binding to Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards cRARbeta2 receptor by displacing 0.82 nM 3[H]all-trans-RAMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity for retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.520nMAssay Description:Transactivation of mouse Gal4-fused RARbeta-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMAssay Description:Transactivation of GAL4-fused mouse RARgamma-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity towards human Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Binding affinity against Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity against Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoic acid receptor gamma using transactivatio...More data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Inhibition of [3H]ATRA-Hl60 binding to Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Binding affinity for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of [3H]-ATRA-Hl60 binding to Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.940nMAssay Description:Binding affinity for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Compound was tested for binding affinity against retinoic acid receptor using 5 nM of [3H]RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Transactivation of human Gal4-DBD-fused RARalpha-LBD expressed in HEK293T cells after 16 to 24 hrs by FRET based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Transactivation of GAL4-fused mouse RARalpha-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Transactivation of GAL4-fused mouse RARbeta-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity for retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Transcriptional activation of retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Transactivation of mouse Gal4-fused RARalpha-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
TargetCellular retinoic acid-binding protein 2(Mouse)
University of Alabama At Birmingham
Curated by ChEMBL
University of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Inhibition of [3H]ATRA binding to murine Cytoplasmic retinoic acid binding protein (CRABP) type 2More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
