BDBM329560 2-(5-(2-methyl-4- (((1S,2S)-2-(3- methylpyridin-2- yl)cyclopropyl)methoxy) pyrimidin-5-yl)pyridin- 2-yl)propan-2-ol (enantiomer B)::US9663513, 173::US9663513, 174

SMILES Cc1ncc(-c2ccc(nc2)C(C)(C)O)c(OC[C@H]2C[C@@H]2c2ncccc2C)n1

InChI Key InChIKey=JJKKLCHWVWSGQV-MSOLQXFVSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329560   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329560(2-(5-(2-methyl-4- (((1S,2S)-2-(3- methylpyridin-2-...)
Affinity DataKi:  0.510nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329560(2-(5-(2-methyl-4- (((1S,2S)-2-(3- methylpyridin-2-...)
Affinity DataKi:  8.42nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent