BDBM330163 5-Chloro-N-[4-[(1S,4R)-5-oxa-2-azabicyclo[2.2.1]heptan-4-yl]phenyl]pyridin-2-amine::US9663530, Example 7

SMILES Clc1ccc(Nc2ccc(cc2)[C@]23CN[C@H](CO2)C3)nc1

InChI Key InChIKey=OCKNSZXCSFMCPG-HOCLYGCPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330163   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM330163(5-Chloro-N-[4-[(1S,4R)-5-oxa-2-azabicyclo[2.2.1]he...)
Affinity DataIC50:  309nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM330163(5-Chloro-N-[4-[(1S,4R)-5-oxa-2-azabicyclo[2.2.1]he...)
Affinity DataIC50:  41.4nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent