BDBM335571 N-(3-(1,2,3-thiadiazol-4-yl)phenyl)-5-((4-aminopiperidin-1-yl)methyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine::US9737542, Example 14

SMILES NC1CCN(Cc2ccn3ncnc(Nc4cccc(c4)-c4csnn4)c23)CC1

InChI Key InChIKey=KWTURSVJCRVIJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335571   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335571(N-(3-(1,2,3-thiadiazol-4-yl)phenyl)-5-((4-aminopip...)
Affinity DataIC50:  550nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent