BDBM336811 6-((((S)-1-amino-1-oxopropan- 2-yl)amino)methyl)-2-(4-(4- trifluoromethyl)phenoxy)cyclohex- 1-en-1-yl)pyrimidine- 4-carboxamide::US9745287, Compound 57

SMILES C[C@H](NCc1cc(nc(n1)C1=CCC(CC1)Oc1ccc(cc1)C(F)(F)F)C(N)=O)C(N)=O

InChI Key InChIKey=UDOHHODQWOMOFC-HKALDPMFSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336811   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM336811(6-((((S)-1-amino-1-oxopropan- 2-yl)amino)methyl)-2...)
Affinity DataKi:  175nMAssay Description:Cells Manual Electrophysiology: The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DME...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM336811(6-((((S)-1-amino-1-oxopropan- 2-yl)amino)methyl)-2...)
Affinity DataIC50:  557nMAssay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent