BDBM338466 (7R)-2-[[2,5-difluoro-4-[4-(1,2,4- triazol-4-yl)-1- piperidyl]phenyl]methyl]-7-phenyl- thiazepane 1,1-dioxide::US9751873, Example 153

SMILES Fc1cc(N2CCC(CC2)n2cnnc2)c(F)cc1CN1CCCC[C@H](c2ccccc2)S1(=O)=O

InChI Key InChIKey=XSCYOZQLTUWZCU-RUZDIDTESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338466   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM338466((7R)-2-[[2,5-difluoro-4-[4-(1,2,4- triazol-4-yl)-1...)
Affinity DataIC50:  4nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent