BDBM339029 US10201546, Example 3

SMILES Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(Cl)c(CN3CCOCC3)c(Cl)c2c1

InChI Key InChIKey=YRKBJRITGFDVIS-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 339029   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM339029(US10201546, Example 3)
Affinity DataIC50:  1.80E+3nMAssay Description:For the RORγt construct used in the ThermoFluorŪ assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM339029(US10201546, Example 3)
Affinity DataKd:  100nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent