BDBM341243 (S)-4-(2-(1-(2,6-diamino-5-cyanopyrimidin-4-yl)pyrrolidin-2-yl)-4-oxo-3-phenyl-3,4-dihydroquinazolin-5-yl)butanoic acid ::US9765060, Compound 70
SMILES Nc1nc(N)c(C#N)c(n1)N1CCC[C@H]1c1nc2cccc(CCCC(O)=O)c2c(=O)n1-c1ccccc1
InChI Key InChIKey=WDKDKOGDFAMTQW-FQEVSTJZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341243
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 3nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair