BDBM345005 1-{2-[(3S)-3-::1-{2-[(3S)-3-fluoropyrrolidin-1-yl]-2-oxoethyl}-3-(1-phenyl-1H-indazol-4-yl)imidazolidin-2-one::US9783527, Example 307

SMILES F[C@H]1CCN(C1)C(=O)CN1CCN(C1=O)c1cccc2n(ncc12)-c1ccccc1

InChI Key InChIKey=WANHSWIMMJEFCO-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 345005   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345005(1-{2-[(3S)-3- | 1-{2-[(3S)-3-fluoropyrrolidin-1-yl...)
Affinity DataIC50:  1.42E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345005(1-{2-[(3S)-3- | 1-{2-[(3S)-3-fluoropyrrolidin-1-yl...)
Affinity DataIC50:  520nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent