BDBM345251 (1r,4r)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 4-(1-methyl-1H-indazol-6- yl)cyclohexanecarboxamide::US9783488, Example 104

SMILES Cc1c(F)cccc1[C@@]1(CC[C@@H](CC1)c1ccc2cnn(C)c2c1)C(=O)NO

InChI Key InChIKey=WPUFWHGXUIRYPU-VVONHTQRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345251   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM345251((1r,4r)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 4-...)
Affinity DataIC50:  950nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent