BDBM347746 (Z)-N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-4-methyl-5-(5-morpholinopent-2-en-3-yl)thiophene-3-carboxamide::US9790212, Example 71

SMILES C\C=C(\CCN1CCOCC1)c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C

InChI Key InChIKey=RQHHTQQZIPZYKU-DVZOWYKESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347746   

LigandPNGBDBM347746((Z)-N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent