BDBM349998 (R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)ethyl)-4- methyl-2- (methylamino)pentanamide::US10208023, No. 16

SMILES CN[C@H](CC(C)C)C(=O)NCCOc1cc(F)cc(c1)C(F)(F)F

InChI Key InChIKey=WDZZOYIYBCSHHF-CQSZACIVSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 349998   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  9.62E+3nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  1.50E+4nMAssay Description:In some cases, the potency of compounds was measured using either the Patchliner automated patch clamp platform (Nanion) or manual patch clamp techni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  3.50E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Manual Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  1.50E+4nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (0.25HZ Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  2.32E+4nMAssay Description:NAV1.7 INWARD CURRENT BLOCK (nM) (7HZ Manual Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM349998((R)-N-(2-(3-fluoro-5- (trifluoromethyl)phenoxy)eth...)
Affinity DataIC50:  8.12E+3nMAssay Description:NAV1.7 SLOW INACTIVATION BLOCK (nM) (Automated Patchclamp).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent