BDBM354708 Preparation of 4-((2S,5R)-5-((R)-2,2,2-trifluoro-1-hydroxyethyl)-2-(trifluoromethyl)oxazolidin-3-yl)-2-(trifluoromethyl)benzonitrile::US9809583, Example 21

SMILES O[C@H]([C@H]1CN([C@@H](O1)C(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=CODCZUURZSYJCY-MXWKQRLJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354708   

TargetAndrogen receptor(Chlorocebus sabaeus (Green monkey) (Cercopithecus ...)
Dong-A St

US Patent
LigandPNGBDBM354708(Preparation of 4-((2S,5R)-5-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50:  1.06E+3nMAssay Description:In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent