BDBM354841 6-(4-amino-3- methoxyphenyl)-1- cyclopentyl-1H- imidazo[4,5-b]pyrazin- 2(3H)-one::US9814704, Example 118

SMILES COc1cc(cnc1N)-c1cnc2[nH]c(=O)n(C3CCCC3)c2n1

InChI Key InChIKey=QAYATWJCROUOHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354841   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester

US Patent
LigandPNGBDBM354841(6-(4-amino-3- methoxyphenyl)-1- cyclopentyl-1H- im...)
Affinity DataIC50:  550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent