BDBM354841 6-(4-amino-3- methoxyphenyl)-1- cyclopentyl-1H- imidazo[4,5-b]pyrazin- 2(3H)-one::US9814704, Example 118
SMILES COc1cc(cnc1N)-c1cnc2[nH]c(=O)n(C3CCCC3)c2n1
InChI Key InChIKey=QAYATWJCROUOHW-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 354841
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester
US Patent
The University of Rochester
US Patent
Affinity DataIC50: 550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair