BDBM359974 N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperidin-1-yl]pyridin-3-yl}-2-(cis-2-methylcyclopropyl)furo[2,3-b]pyridine-6-carboxamide (Example 73) and N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperidin-1-yl]pyridin-3-yl}-2-(trans-2-methylcyclopropyl)furo[2,3-b]pyridine-6-carboxamide (Example 74)::US9822124, Example 73
SMILES CC1CC1c1cc2ccc(nc2o1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1
InChI Key InChIKey=IJRCFRJEESBYIJ-NBFQZJGRSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 359974
Affinity DataIC50: <10nMAssay Description:Pim-1 and Pim-3 kinase assays 20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Pim-1 and Pim-3 kinase assays 20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Pim-2 kinase assay20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay buffer ...More data for this Ligand-Target Pair