BDBM360844 Phenyl (2-(2H-1,2,3-Triazol-2-yl)phenyl)((2R, 5R)-2-methyl-5-(5-phenyloxazol-2-yl)piperidin-1- yl)methanone::US9828368, Example 74

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)c1ncc(o1)-c1ccccc1

InChI Key InChIKey=MDSNTQQWLZVEPX-IEBWSBKVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 360844   

TargetOrexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360844(Phenyl (2-(2H-1,2,3-Triazol-2-yl)phenyl)((2R, 5R)-...)
Affinity DataIC50:  55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360844(Phenyl (2-(2H-1,2,3-Triazol-2-yl)phenyl)((2R, 5R)-...)
Affinity DataIC50:  111nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent