BDBM362876 (S)-2-((-4-ethoxycyclohexyl)methyl)-N-((R)-1-(4-(ethylsulfonyl)phenyl)-2-hydroxyethyl)-1-isopropylisoindoline-5-carboxamide (8a) and (8b)::US9845308, Example 8a

SMILES CCO[C@H]1CC[C@H](CN2Cc3cc(ccc3[C@@H]2C(C)C)C(=O)N[C@@H](CO)c2ccc(cc2)S(=O)(=O)CC)CC1

InChI Key InChIKey=BVXCNIOMDHVQKU-DAJOFOPLSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362876   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM362876((S)-2-((-4-ethoxycyclohexyl)methyl)-N-((R)-1-(4-(e...)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent