BDBM363197 6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]-5-[5-({[(3- methylphenyl)amino]carbonyl} amino)-1-benzothien-2- yl]nicotinamide::US10633373, Example 1::US10669265, Example 1::US9868726, Example 1

SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(C)(C)=O)c1

InChI Key InChIKey=ABDRBGWMJSCIGC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 363197   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM363197(6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...)
Affinity DataIC50:  8nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM363197(6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...)
Affinity DataIC50:  20nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM363197(6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...)
Affinity DataIC50:  8nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM363197(6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...)
Affinity DataIC50:  20nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM363197(6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...)
Affinity DataIC50:  8nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM363197(6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...)
Affinity DataIC50:  20nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM363197(6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...)
Affinity DataIC50:  20nMAssay Description:PDGFRβ: Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent