BDBM36399 CID10221335::N-[2-(6-Amino-4-methylpyridin-2-yl)ethyl]-4-cyanobenzamide, 8

SMILES Cc1cc(N)nc(CCNC(=O)c2ccc(cc2)C#N)c1

InChI Key InChIKey=QINCZVSBLITNRD-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36399   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36399(CID10221335 | N-[2-(6-Amino-4-methylpyridin-2-yl)e...)
Affinity DataIC50:  120nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36399(CID10221335 | N-[2-(6-Amino-4-methylpyridin-2-yl)e...)
Affinity DataIC50:  790nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36399(CID10221335 | N-[2-(6-Amino-4-methylpyridin-2-yl)e...)
Affinity DataIC50:  7.40E+3nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed