BDBM365347 2-(2-aminopyridin-3-yl)-N-(3- methylphenyl)-1- benzothiophene-5- carboxamide::US10633373, Example 48::US10669265, Example 48::US9868726, Example 48

SMILES Cc1cccc(NC(=O)c2ccc3sc(cc3c2)-c2cccnc2N)c1

InChI Key InChIKey=IPDANOJCSZJIMQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 365347   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365347(2-(2-aminopyridin-3-yl)-N-(3- methylphenyl)-1- ben...)
Affinity DataIC50:  3.57E+3nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365347(2-(2-aminopyridin-3-yl)-N-(3- methylphenyl)-1- ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365347(2-(2-aminopyridin-3-yl)-N-(3- methylphenyl)-1- ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365347(2-(2-aminopyridin-3-yl)-N-(3- methylphenyl)-1- ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:PDGFRβ: Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365347(2-(2-aminopyridin-3-yl)-N-(3- methylphenyl)-1- ben...)
Affinity DataIC50:  3.57E+3nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365347(2-(2-aminopyridin-3-yl)-N-(3- methylphenyl)-1- ben...)
Affinity DataIC50:  3.57E+3nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent