BDBM365349 US10633373, Example 54::US10669265, Example 54::US9868726, Example 54::methyl 5-[N-({6-amino-5-[5- ({[(2-fluoro-5- methylphenyl)amino]carbonyl} amino)-1-benzothien-2- yl]pyridin-3-yl}carbonyl)-S- methylsulfonimidoyl]pentanoate

SMILES COC(=O)CCCC[S@](C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(C)ccc3F)ccc2s1

InChI Key InChIKey=KPVSGWFUYLJRIW-WBCKFURZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 365349   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365349(US10633373, Example 54 | US10669265, Example 54 | ...)
Affinity DataIC50:  3nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365349(US10633373, Example 54 | US10669265, Example 54 | ...)
Affinity DataIC50:  3nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365349(US10633373, Example 54 | US10669265, Example 54 | ...)
Affinity DataIC50:  3nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent