BDBM373709 US10246444, Example 86
SMILES OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C[C@H]1CCSS1
InChI Key InChIKey=KVMBBUXCOHWOBJ-XZOQPEGZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 373709
Affinity DataKd: 50nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Sabila Biosciences
US Patent
Sabila Biosciences
US Patent
Affinity DataKd: >1.00E+4nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-751,753-758,760-1210](Homo sapiens (Human))
Sabila Biosciences
US Patent
Sabila Biosciences
US Patent
Affinity DataKd: 50nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-745,747-749,751-1210](Homo sapiens (Human))
Sabila Biosciences
US Patent
Sabila Biosciences
US Patent
Affinity DataKd: 50nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair