BDBM374625 1-(1-(2,4-Dichlorophenyl)ethyl)-6-(3′-ethyl-[1,4′-bipiperidin]-1′-yl)-1H-pyrazolo[3,4-b]pyrazine-3-carboxamide hydrochloride::US10246462, Example 6

SMILES CCC1CN(CCC1N1CCCCC1)c1cnc2c(nn(C(C)c3ccc(Cl)cc3Cl)c2n1)C(N)=O

InChI Key InChIKey=IAAYIZTZZHMMNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 374625   

TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Flx Bio

US Patent
LigandPNGBDBM374625(1-(1-(2,4-Dichlorophenyl)ethyl)-6-(3′-ethyl-...)
Affinity DataIC50:  300nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent