BDBM376090 5-(2-fluoro-5-(pyrimidin-2-yl)- 4- (trifluoromethyl)benzamido)- 1-(4-fluorophenyl)-N-methyl- 1H-pyrazole-3-carboxamide::US9914736, Compound 86

SMILES CNC(=O)c1cc(NC(=O)c2cc(-c3ncccn3)c(cc2F)C(F)(F)F)n(n1)-c1ccc(F)cc1

InChI Key InChIKey=CWSAWCFYGWGVFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376090   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376090(5-(2-fluoro-5-(pyrimidin-2-yl)- 4- (trifluoromethy...)
Affinity DataIC50:  7nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent