BDBM376092 N-(3-(azetidine-1-carbonyl)-1- (4-fluorophenyl)-1H-pyrazol- 5-yl)-2-fluoro-5-(pyrimidin-2- yl)-4- (trifluoromethyl)benzamide::US9914736, Compound 88

SMILES Fc1ccc(cc1)-n1nc(cc1NC(=O)c1cc(-c2ncccn2)c(cc1F)C(F)(F)F)C(=O)N1CCC1

InChI Key InChIKey=GFWUSYDZPKBSSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376092   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM376092(N-(3-(azetidine-1-carbonyl)-1- (4-fluorophenyl)-1H...)
Affinity DataIC50:  14nMAssay Description: In this assay, U2OS cells express the human TrkA receptor as a fusion with the weakly complementing fragment of B-galactosidase, which DiscoverX cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent