BDBM377592 4-{[(1S)-1-(6-chloro-2-oxo-::US10266495, Compound I-4

SMILES CS(=O)(=O)c1cc(ccc1NCc1cc2cc(Cl)ccc2[nH]c1=O)C#N

InChI Key InChIKey=DAMMQCSIHDORSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377592   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM377592(4-{[(1S)-1-(6-chloro-2-oxo- | US10266495, Compound...)
Affinity DataIC50: >1.00E+3nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent