BDBM383417 1-(2,4-difluorophenyl)-N- (((5R,8S)-3-(2,6-difluorophenyl)- 9,9-dimethyl-5,6,7,8-tetrahydro- 5,8-methanocinnolin-8- yl)methyl)-N- ethylmethanesulfonamide::US10280144, Compound 133

SMILES CCN(C[C@@]12CC[C@@H](c3cc(nnc13)-c1c(F)cccc1F)C2(C)C)S(=O)(=O)Cc1ccc(F)cc1F

InChI Key InChIKey=ZJGHSVQDIZMSEV-PPHZAIPVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383417   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383417(1-(2,4-difluorophenyl)-N- (((5R,8S)-3-(2,6-difluor...)
Affinity DataIC50:  2.60nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent