BDBM384538 (R)-N-(1-((1-acryloylpyrrolidin-2-yl)methyl)-5-(((cyclopropylmethyl)amino)methyl)-1H-benzo[d]imidazol-2-yl)-5-(oxazol-5-yl)thiophene-2-carboxamide::US9932329, Cpd # 9
SMILES C=CC(=O)N1CCC[C@@H]1Cn1c(NC(=O)c2ccc(s2)-c2cnco2)nc2cc(CNCC3CC3)ccc12
InChI Key InChIKey=ZEJMFFQWPNGDLL-HXUWFJFHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 384538
Affinity DataIC50: 0.300nMAssay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair