BDBM388731 N-[(1S)-2-(Dimethylamino)-1-methyl-2-oxoethyl]-5-[3-(1-quinolin-6-ylcyclopropyl)imidazo[1,2-a]pyrimidin-6-yl]pyridine-2-carboxamide::US10738052, Example 61::US11261191, Example 61::US9944645, 61

SMILES C[C@H](NC(=O)c1ccc(cn1)-c1cnc2ncc(n2c1)C1(CC1)c1ccc2ncccc2c1)C(=O)N(C)C

InChI Key InChIKey=MGZIVYAOPUBKAZ-SFHVURJKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 388731   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM388731(N-[(1S)-2-(Dimethylamino)-1-methyl-2-oxoethyl]-5-[...)
Affinity DataIC50: <500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM388731(N-[(1S)-2-(Dimethylamino)-1-methyl-2-oxoethyl]-5-[...)
Affinity DataIC50: <500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM388731(N-[(1S)-2-(Dimethylamino)-1-methyl-2-oxoethyl]-5-[...)
Affinity DataIC50: <500nMAssay Description:Briefly, histidine-tagged c-Met catalytic domain fusion protein was used for the assay. IC50 measurements were based on the degree of phosphorylation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent