BDBM393581 US9969687, Compound 257

SMILES CCc1c(OC)cncc1N1C(=O)c2c(C1=O)c(NS(=O)(=O)c1ccc(cc1)C(C)(C)C)ccc2Cl

InChI Key InChIKey=BIZCMRZLYLYWDA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 393581   

TargetC-C chemokine receptor type 9(Homo sapiens (Human))
Norgine

US Patent
LigandPNGBDBM393581(US9969687, Compound 257)
Affinity DataKi:  21nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 9(Homo sapiens (Human))
Norgine

US Patent
LigandPNGBDBM393581(US9969687, Compound 257)
Affinity DataKi:  25nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed