BDBM394485 Enantiomer 1 and Enantiomer 2 of (trans-4a,8a)-2-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)decahydroisoquinolin-4a-ol::US10308614, Example 85

SMILES Nc1nnc(cc1N1CC[C@]2(O)CCCC[C@@H]2C1)-c1ccccc1O

InChI Key InChIKey=CIYLCQZYHHBUOV-BFUOFWGJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394485   

TargetTranscription activator BRG1 [1448-1575](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM394485(Enantiomer 1 and Enantiomer 2 of (trans-4a,8a)-2-(...)
Affinity DataIC50:  11nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent