BDBM3948 12-phenyl-4,6-dioxa-10,12-diazatricyclo[7.3.0.0^{3,7}]dodeca-1,3(7),8,10-tetraene::5,6-Methylenedioxy-1-phenylbenzimidazole Hydrochloride::5-Substituted 1-Phenylbenzimidazole 37

SMILES C1Oc2cc3ncn(-c4ccccc4)c3cc2O1

InChI Key InChIKey=IDYRCYDXFSHXAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3948   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM3948(12-phenyl-4,6-dioxa-10,12-diazatricyclo[7.3.0.0^{3...)
Affinity DataIC50:  2.20E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM3948(12-phenyl-4,6-dioxa-10,12-diazatricyclo[7.3.0.0^{3...)
Affinity DataIC50: >5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM3948(12-phenyl-4,6-dioxa-10,12-diazatricyclo[7.3.0.0^{3...)
Affinity DataIC50:  2.70E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed