BDBM402777 N-(2-bromophenyl)-2- [(1S,4S)- or (1R,4R)-2,5- diazabicyclo[2.2.2]oct-2- yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 84

SMILES Brc1ccccc1NC(=O)c1ccc2cnc(nn12)N1C[C@@H]2CC[C@H]1CN2

InChI Key InChIKey=JEWHEEPUTSENKI-STQMWFEESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402777   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402777(N-(2-bromophenyl)-2- [(1S,4S)- or (1R,4R)-2,5- dia...)
Affinity DataIC50:  7.81E+3nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent