BDBM410078 D2574::US10370360, Example 30

SMILES CC1Cc2ccc(cc2CN1c1cncnc1)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C(F)(F)F

InChI Key InChIKey=GCCXSOBNEILODC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 410078   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM410078(D2574 | US10370360, Example 30)
Affinity DataIC50:  544nMAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a Lantha Screen Eu kinase activity assay technology (Invitrogen, USA). K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM410078(D2574 | US10370360, Example 30)
Affinity DataIC50: >1.00E+4nMAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a Lantha Screen Eu kinase activity assay technology (Invitrogen, USA). K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM410078(D2574 | US10370360, Example 30)
Affinity DataIC50: >1.00E+4nMAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a Lantha Screen Eu kinase activity assay technology (Invitrogen, USA). K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
The Board of Regents of The University of Texas System

US Patent
LigandPNGBDBM410078(D2574 | US10370360, Example 30)
Affinity DataIC50:  7.60E+3nMAssay Description:The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a Lantha Screen Eu kinase activity assay technology (Invitrogen, USA). K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent