BDBM414761 N-(3-Fluoro-5-methyl-4-(3- (1-methyl-1H-pyrazol-4-yl)- 1H-pyrazolo[3,4-c]pyridin- 5-yl)benzyl)propan-2-amine::US10435405, Example 178::US10934288, Example 178

SMILES CC(C)NCc1cc(C)c(c(F)c1)-c1cc2c(n[nH]c2cn1)-c1cnn(C)c1

InChI Key InChIKey=AYOOVMBNRYNFMG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414761   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM414761(N-(3-Fluoro-5-methyl-4-(3- (1-methyl-1H-pyrazol-4-...)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM414761(N-(3-Fluoro-5-methyl-4-(3- (1-methyl-1H-pyrazol-4-...)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent