BDBM419624 US10464911, Example 52

SMILES CCN1[C@@H](C)CN(C[C@H]1C)S(=O)(=O)N(Cc1ccc(cn1)-c1nnc(o1)C(F)F)c1ccccc1

InChI Key InChIKey=MPQLERWNCCSZSP-CALCHBBNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419624   

TargetHistone deacetylase 1(Homo sapiens (Human))
Chong Kun Dang Pharmaceutical

US Patent
LigandPNGBDBM419624(US10464911, Example 52)
Affinity DataIC50:  61nMAssay Description:HDAC enzyme activity was measured using a HDAC Fluorimetric Drug Discovery Kit (BML-AK511, 516, Enzo Life Science). For the HDAC1 enzyme activity tes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Chong Kun Dang Pharmaceutical

US Patent
LigandPNGBDBM419624(US10464911, Example 52)
Affinity DataIC50:  1.16E+5nMAssay Description:HDAC enzyme activity was measured using a HDAC Fluorimetric Drug Discovery Kit (BML-AK511, 516, Enzo Life Science). For the HDAC1 enzyme activity tes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent