BDBM432109 (S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4- fluorophenyl)methyl- d)-N6-ethyl-N4- neopentylquinazoline- 4,6-diamine::US10577352, Compound I-6

SMILES CCN(C(c1cn(nn1)C1CC1)c1ccc(F)cc1)c1ccc2ncnc(NCC(C)(C)C)c2c1

InChI Key InChIKey=BTTKRWWCCQEAES-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 432109   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM432109((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...)
Affinity DataEC50:  4.23E+3nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM432109((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...)
Affinity DataIC50:  276nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent