BDBM433090 5-cyclopropyl-N-((1R,3r,5S)-8-((4-((4,4,4- trifluorobutyl)amino)piperidin-1- yl)sulfonyl)-8-azabicyclo[3.2.1]octan-3- yl)isoxazole-3-carboxamide::US10577363, Compound 794

SMILES FC(F)(F)CCCNC1CCN(CC1)S(=O)(=O)N1[C@H]2CC[C@@H]1C[C@@H](C2)NC(=O)c1cc(on1)C1CC1

InChI Key InChIKey=BPSSCBRUCNPVEJ-REPLKXPHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433090   

TargetHistone-lysine N-methyltransferase SMYD3(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM433090(5-cyclopropyl-N-((1R,3r,5S)-8-((4-((4,4,4- trifluo...)
Affinity DataIC50:  1.87nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent