BDBM433661 5-[3-(5-Chloro-3-methylpyridin-2-yl)-3-fluoropiperidine-1-carbonyl]-N,N-dimethylpyridazin-3-amine::US10562882, Example 39

SMILES CN(C)c1cc(cnn1)C(=O)N1CCCC(F)(C1)c1ncc(Cl)cc1C

InChI Key InChIKey=HSYSLPZHRCFBQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433661   

TargetProkineticin receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM433661(5-[3-(5-Chloro-3-methylpyridin-2-yl)-3-fluoropiper...)
Affinity DataIC50:  400nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent