BDBM440391 US10633389, Example 56-3::US20230279020, Example 56-3

SMILES CCOC(=O)N1CCOC[C@@H]1CNc1nc(nc(-c2c(C)noc2C)c1Cl)-c1cc(OC[C@H](O)CNC)ccc1Cl

InChI Key InChIKey=ZMEFXJFAVLEPMO-ZWKOTPCHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 440391   

TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM440391(US10633389, Example 56-3 | US20230279020, Example ...)
Affinity DataIC50: <100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween 20, prepared on the day of use...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM440391(US10633389, Example 56-3 | US20230279020, Example ...)
Affinity DataIC50: <100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween 20, prepared on the day of use...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent