BDBM441089 US10640495, Example I-236::US10640495, Example I-97

SMILES COCC[C@@H]1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2)-c2cnc3n(C)ncc3c2)[C@@H](O1)c1ccnc(F)c1

InChI Key InChIKey=VVVYQGICZDMAMH-OASJLCFRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 441089   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM441089(US10640495, Example I-236 | US10640495, Example I-...)
Affinity DataIC50: <100nMAssay Description:Seven point five μL per well of human TrkA (PV3144, Lifetechnologies, final concentration: 1 nmol/L) suspended in the assay buffer (100 mmol/L 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM441089(US10640495, Example I-236 | US10640495, Example I-...)
Affinity DataIC50:  1.40nMAssay Description:Seven point five μL per well of human TrkA (PV3144, Lifetechnologies, final concentration: 1 nmol/L) suspended in the assay buffer (100 mmol/L 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent