BDBM445393 (S)-8-isopropyl-5-methyl-7-(2-(((S)-1-(1-(4-trifluoromethylphenyl)-1H-imidazol-4-yl)ethyl)amino)pyrimidin-4-yl)-2-oxa-5,7-diazaspiro[3.4]oct-6-one::US10682352, Compound 106::US10682352, Compound 107
SMILES CC(C)[C@@H]1N(C(=O)N(C)C11COC1)c1ccnc(N[C@@H](C)c2cn(cn2)-c2ccc(cc2)C(F)(F)F)n1
InChI Key InChIKey=MNXGUCXNQJSJNL-KKSFZXQISA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 445393
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical
US Patent
Shanghai Haihe Pharmaceutical
US Patent
Affinity DataIC50: <100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical
US Patent
Shanghai Haihe Pharmaceutical
US Patent
Affinity DataIC50: <100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair