BDBM446056 US10669246, Example 107::US10968188, Example 107

SMILES Cc1ccc(-c2ccc3nc(NC(=O)[C@@H]4C[C@@H]4F)sc3c2)c2cn[nH]c12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 446056   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM446056(US10669246, Example 107 | US10968188, Example 107)
Affinity DataIC50:  14.8nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM446056(US10669246, Example 107 | US10968188, Example 107)
Affinity DataIC50:  14.8nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent