BDBM449002 2-[4-(4-aminopiperidin-1-yl)-2-(dimethylamino)-5-(3-fluoro-5-methylphenyl)pyridin-3-yl]-4-methoxy-1H-1,3-benzodiazole-6-carbonitrile ::US10696689, Compound 1-3::US11186590, Compound 1-3

SMILES COc1cc(cc2nc([nH]c12)-c1c(ncc(-c2cc(C)cc(F)c2)c1N1CCC(N)CC1)N(C)C)C#N

InChI Key InChIKey=MNTYWCOOZNFBOW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449002   

TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM449002(2-[4-(4-aminopiperidin-1-yl)-2-(dimethylamino)-5-(...)
Affinity DataEC50: >1nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human somatostatin receptor subtype 2 ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM449002(2-[4-(4-aminopiperidin-1-yl)-2-(dimethylamino)-5-(...)
Affinity DataEC50: >1nMAssay Description:On the day of the assay, the media is aspirated and the cells are treated with 50 μL of 1.6 μM NKH477 (Sigma # N3290) plus various dilution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent