BDBM49766 MLS000708948::N-(3-imidazol-1-ylpropyl)-5-phenyl-1,2-oxazole-3-carboxamide::N-(3-imidazol-1-ylpropyl)-5-phenyl-isoxazole-3-carboxamide::N-[3-(1-imidazolyl)propyl]-5-phenyl-3-isoxazolecarboxamide::SMR000289715::cid_2962284
SMILES O=C(NCCCn1ccnc1)c1cc(on1)-c1ccccc1
InChI Key InChIKey=FLWZIODGHJAZJD-UHFFFAOYSA-N
Data 5 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 49766
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 7.72E+3nMAssay Description:Activation of GFP-tagged HIF1alpha expressed in human U2OS cells assessed as HIF1alpha nuclear translocation by high content imaging assayMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 1.58E+4nMAssay Description:Activation of human HIF1alpha expressed in human U2OS cells assessed as increase in VEGF expression by RT-PCR analysisMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: 6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
Affinity DataEC50: 1.37E+6nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 8.67E+3nMAssay Description:Activation of human HIF1alpha expressed in DFX-induced human U2OS cells incubated for 30 mins prior to DFX-induction measured after overnight incubat...More data for this Ligand-Target Pair