BDBM50005478 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-phenol::2-methoxy-5-(3,4,5-trimethoxyphenethyl)phenol::CHEMBL10557

SMILES COc1ccc(CCc2cc(OC)c(OC)c(OC)c2)cc1O

InChI Key InChIKey=UXDFUVFNIAJEGM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50005478   

TargetTubulin beta-2B chain(Bos taurus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  630nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibition of purified bovine brain tubulin polymerisation in the absence of microtubule-associated proteins.More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  3.50E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  6.57E+4nMAssay Description:Inhibition of precipitation of human soluble CD69 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  3.30E+3nMAssay Description:Ability to inhibit Tubulin polymerization in Bovine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  630nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed