BDBM50006616 CHEMBL3235484

SMILES Fc1ccc(N2CCN3CCC2CC3)c2-c3ccccc3S(=O)(=O)c12

InChI Key InChIKey=WITLOMKPGROHOE-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50006616   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006616(CHEMBL3235484)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat cortical membrane alpha7-nAChR after 150 mins by gamma-counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006616(CHEMBL3235484)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006616(CHEMBL3235484)
Affinity DataKi:  261nMAssay Description:Displacement of [3H]epibatidine from alpha3beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006616(CHEMBL3235484)
Affinity DataKi:  562nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006616(CHEMBL3235484)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006616(CHEMBL3235484)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006616(CHEMBL3235484)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha2beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed