BDBM50014095 CHEMBL3260850

SMILES Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2cccc(Cl)c2)on1

InChI Key InChIKey=LITPAOYSUGZCNV-ZBFHGGJFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014095   

Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))TBA
LigandPNGBDBM50014095(CHEMBL3260850)
Affinity DataIC50:  1.17E+5nMAssay Description:Binding affinity to VHL E3 ligase (unknown origin) by fluorescence polarization (FP) assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetElongin-B/Elongin-C/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50014095(CHEMBL3260850)
Affinity DataIC50:  1.17E+5nMAssay Description:Displacement of FAM-DEALAHyp-YIPD from 6xHis-tagged VHL (1 to 213)/elongins-B/elonginC (unknown origin) expressed in Escherichia coli BL21 after 1 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed