BDBM50014151 ((1S,2R,3R,4S)-1-Benzyl-4-tert-butoxycarbonylamino-2,3-dihydroxy-5-phenyl-pentyl)-carbamic acid tert-butyl ester::CHEMBL9618::di-tert-butyl ((2S,3R,4R,5S)-3,4-dihydroxy-1,6-diphenylhexane-2,5-diyl)dicarbamate

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=XEFORNHNQOHGSE-CJRSTVEYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50014151   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50014151(((1S,2R,3R,4S)-1-Benzyl-4-tert-butoxycarbonylamino...)
Affinity DataKi:  40nMAssay Description:Binding affinity to HIV-1 proteaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50014151(((1S,2R,3R,4S)-1-Benzyl-4-tert-butoxycarbonylamino...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50014151(((1S,2R,3R,4S)-1-Benzyl-4-tert-butoxycarbonylamino...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of HIV-1 protease was determined in vitroChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50014151(((1S,2R,3R,4S)-1-Benzyl-4-tert-butoxycarbonylamino...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against recombinant HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50014151(((1S,2R,3R,4S)-1-Benzyl-4-tert-butoxycarbonylamino...)
Affinity DataIC50:  280nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed