BDBM50022387 2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido[3,2-d]pyrimidin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid::CHEMBL36639

SMILES Nc1nc2CCC(CNc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)Nc2c(=O)[nH]1

InChI Key InChIKey=HLQVKHILGYCUSU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022387   

TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed